Sequel Ace

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Successor to the late Sequel Pro, it still manages to be an unapologetically macOS application and a powerful database manager. Easy to use, responsive, stable. All the frequent stuff you need to do is in the UI, plus of course you can write your own queries when you need to. It can connect directly to a MySQL/MariaDB database or set up its own SSH tunnel.

Sequel Ace and its predecessor are the only database GUIs I’ve actually liked rather than merely tolerated. If it ran on Linux, or if it could talk to Microsoft SQL Server, it’s the only one I would use. It’s that good.

More info at Sequel Ace.