Category: Life

Posted on
by

Looks like IEEE has finally renamed their sustainable tech conference. Now it’s “IEEE SustainTech Expo.” Not only is it a bit clearer than the old name, but ever since Among Us came out, “SusTech” always made me giggle a bit. I doubt I was the only one.

Update: apparently I was mistaken, and SustainTech is entirely separate from SusTech, which is still going on. Looking at it a bit more, it seems that SustainTech is more of a marketing/trade show, while SusTech continues to be a technical conference.

Posted on
by

It was hazy, and the weather forecast was partly cloudy, but the sun stayed visible and the eclipse glasses (used here for the photo) haven’t cracked!

Yellow-orange circle on a black background, with a circular chunk apparently cut out of it.

We didn’t do anything complicated this time: just took the glasses with us as we went about our morning, looking through the glasses every 15-20 minutes to see how much was covered until it reached its maximum coverage of 78% of the sun’s apparent diameter.

And at projections. Leaves are nature’s original pinhole camera!

A bunch of overlapping bright crescents of light on the ground.

A road trip like 2017 to see the full annular eclipse would have been cool, but it just wasn’t something we could do this time around, and with clear visibility, there wasn’t any need to seek higher ground like 2012.

Here’s peak coverage for this area, again viewed through eclipse glasses.

Yellow-orange crescent on a black background.

Posted on
by

It’s been 18 years since drug companies replaced pseudoephedrine with phenylephrine to keep their cold medications available over the counter when the people waging War On Drugs(tm) decided to restrict the main ingredient in Sudafed (and what it was named after) because it could be used to make meth.

Though I remember some other decongestant plugging the idea that “unlike those medications, we chose not to change our formulation…” Yeah, because you weren’t using an ingredient that got semi-banned!

From the start, the new formulation clearly wasn’t as effective. When I found out that I could still buy the real medication as long as I asked at the pharmacy counter (and showed ID so that the DEA or whoever knows I’m not trying to get around limits by hitting every pharmacy in town), I stopped bothering with the OTC versions entirely.

I wasn’t surprised when studies showed that phenylephrine doesn’t work.

Back in 2015.

(Restricting sales of the real stuff didn’t seem to make much of a dent in the meth problem, either.)

“Only” eight years later, the FDA reached the same conclusion.

And yet the industry is complaining that “if oral phenylephrine were not available over the counter, it would be a significant burden to consumers.”

HOW?????

It doesn’t work. People who buy it are wasting their time and money on snake oil instead of buying a different medication that might actually do something for them. (Not that this is a problem for the supplement industry, where “not evaluated by the FDA” might as well be a selling point.)

We all ended up worse off: cold meds that don’t work, submitting to surveillance to get the meds that do work, and it didn’t even slow down the meth epidemic.

Posted on
by

This is fascinating: Researchers looked at variations in the human leukocyte antigen (HLA) genes of people who had confirmed cases of Covid before the vaccine rollout and also had genetic records on file.

Those with a particular variation were twice as likely to have been asymptomatic.

Having that same variation from both parents made them 8.5 times as likely to have been asymptomatic!

They looked at two more cohorts and found the same results.

And then they looked at T-cells collected before the pandemic, and found that the ones with this allele responded more actively to SARS-COV2, despite never having been exposed to it before. That lends weight to the hypothesis that some people’s immune systems were able to recognize it as similar to more run-of-the-mill coronaviruses.

Next they want to broaden the study more to include people with a wider range of ancestry.

It doesn’t come close to explaining all asymptomatic cases, and they didn’t look at how it might stack with immune responses that are actually targeted at covid (vaccines, prior infections), or whether it also reduces the chances of long-term damage from covid.

But wouldn’t it be great if someone could come up with a supplement based on what this HLA variant produces that’ll cause your immune system to generalize better? Even if it’s just within coronaviruses?

Posted on
by

Tonight, our Star Trek: Deep Space Nine rewatch (on DVD) is up to “Bar Association”, the episode in which Rom leads all of Quark’s employees on a strike to demand better working conditions.

I swear I didn’t time this intentionally, but it seems appropriate!

Ferengi workers don’t want to stop the exploitation. We want to find a way to become the exploiters.
Rom, before deciding he’d rather stop the exploitation